I think its inevitable that a sequel would be made at some point, with the Cold Iron Studios Game in the Works, maybe a Alien Isolation 2 could be more Survival Horror like the Original.
I would like to be able to play the role of a Xenomorph from Face Hugger to say completing a few Egg Morphs... a Xenomorph would have a pretty tough time on its own Surviving Depending on where it is and how many Humans/Synthetics are around... In Space it has a Advantage of the Humans maybe be weary of killing it (Acid Blood/Hull Breach) but on a Outpost thats maybe a different story all together.
I think even a Hadleys Hope Game that gives you the role of a Xenomorph Tasked with taking Colonist back to the Derelict to Produce enough Xenomorph Horde so that you can then OVERRUN Hadleys Hope... i think this would be a Good Bonus Mission.