If we take a look at this map that Ingeniero provided on one of their threads, and we assume its accurate

It shows the Potential for Locations within such a Game, i have added a Circle where the Neomorph Attacks happened, and thus where the body of Hallett and Ankor will be located. So a Video Game mission to Planet 4 would allow for the discovery/exploration of a number of things.
*Lander Crash Site: Not much evidence to be gained, maybe the bodies of Karine, and Ledwood would be in no good condition to figure whats happened, and Farris no doubt would be severely burnt.
*Neomorph Attack Zone: Where the remains of Hallett and Ankor are located.
*Juggernaught Ship: Where a number of clues remains and Neomorph Spores.
*Stream/River just before the passage to the Juggernaught: The location of the Spores that infected Ledwood, but more Spores could be located at various areas near River/Streams.
*The Inner Engineer City: Where we would have the location of many Dead Bombarded Engineers.
*The Hanger/Docking Bay: What is left to discover here? Any Engineer Ships?
*The Crashed Docking Ship: Another place to explore, what condition are the Dead Engineers in here?
*The Cathedral Building: Again maybe one of the Main Locations, where Davids Workshop (some Black Goo) and Experiments are located, the Dead Bodies of Rosenthal, Cole and Oram including the Egg Chamber with plenty of Eggs remaining. Plus likely Walters Body (depending on his condition).
*Other City Buildings: What clues/horrors remain here, was their temporary shelter from the Bombardment in any of these buildings?
*Vast Mountains, Forest and Open Plains: For locations, where the Gamer could be hunted by Xenomorphs/Neomorphs.
*Missing Neomorph: We only saw the death of one, so where is the other? How long do them live and what happens when they Die?
The other Questions Remaining is what became of the Xenomorph/Neomorph Bodies are their remains, do they decompose? Ridley Scott Teased the Xenomorph would Regenerate, which sounds silly, but maybe not if from the remains, they break down and small Egg Spores grow.
So there is certainly a lot of areas to explore....
A game could have the crew split into groups, one group remains at the Landing Site, and a lot depends where this site is located.... do they land close to the Covenant Lander Wreckage? Closer to the City?
While another TWO Group go off to different areas.... The Player taking control of a character within one of these exploring groups who go to one location, are maybe then called for help by those at the Landing Site or other Party Exploring the different area... which when the Player arrives he discovers they have been infected etc...
The Game could offer TWO alternative Characters to select, one a Female and one a Male, like the Original Resident Evil Game, and each Character belongs to a different exploration party. So if you choose Character A you head off to explore the Juggernaught First, get a SOS to help the other Party, or arrive where they are latter (The Cathedral) while if you choose Character B you are off to the City/Cathedral first, maybe you arrive latter at the Juggernaught or witness survivors of this Party running to your location, with Neomorph in pursuit.
If you are Character A, then by the time you reach the Cathedral, you will discover a few of that Party have been infected with Face Huggers, maybe discover the Bodies and Witness Chest Burster.
If you are Character B maybe you discover Orams body and the Egg Cave, see some get Face Hugged and attempt to leave the Cathedral at which point you run into Character A running of from a Neomorph.
So yes a kind of Survival Horror Game could work very well.